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NADH
NADH (Nicotinamide Adenine Dinucleotide – reduced form) is a naturally occurring coenzyme in the body that plays a central role in cellular energy metabolism. It is the bioactive, energy-rich form of NAD⁺, participating directly in the electron transport chain inside the mitochondria. During cellular respiration, NADH donates electrons derived from the breakdown of carbohydrates, fats, and proteins. These electrons drive the production of ATP (adenosine triphosphate)—the fundamental energy currency of all living cells.
As NADH transfers electrons to the respiratory chain, it enables oxidative phosphorylation, the process through which most of the body’s ATP is generated. This makes NADH crucial for the energy supply of the brain, muscles, and organs. Furthermore, NADH acts as a powerful antioxidant, neutralizing free radicals and reducing oxidative stress, which contributes to cellular aging and DNA damage. It also enhances oxygen utilization efficiency in cells and supports optimal mitochondrial performance, making it essential for both energy generation and cellular longevity.
As we age, the natural levels of NAD⁺ and NADH in our body decline, leading to mitochondrial dysfunction, reduced ATP production, and symptoms of fatigue, brain fog, cognitive decline, and slower recovery. Supplementing with NADH has been shown to significantly improve energy levels, particularly in the brain and muscles, helping to restore alertness, mental clarity, and concentration. NADH is especially beneficial for individuals with chronic fatigue, jet lag, poor sleep, or high cognitive demands. It has been studied for its potential in supporting neurological function and improving symptoms in conditions such as chronic fatigue syndrome, Alzheimer’s disease, and Parkinson’s disease. Athletes and physically active individuals may also benefit from NADH supplementation, as it improves endurance and shortens recovery time by enhancing cellular ATP output. As a non-stimulant, naturally occurring molecule, NADH offers a safe, effective pathway to support energy metabolism, protect cellular function, and delay age-related decline.

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